It is not necessary to explain here the importance of overpressure in pharmaceutical facilities. Is a GMP requirement to establish a differential pressure (normally 10-15 Pa) between cleanrooms and adjacent less clean spaces to avoid product contamination....
Air changes per hour (ACH) are defined as the volume per unit time in hours, of air entering a closed space, divided by the total volume of that space. Mathematically is expressed by means of this simple equation:...
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